Compound Collection Enhancement strategy: Bayer

Take a look at a Big-Pharma approach toward the enhancement of their screening library: The Next Generation Library Initiative (NGLI) at Bayer — against all odds? at
https://doi.org/10.1016/j.drudis.2018.12.003

It describes how Bayer’s HTS collection was increased by 500 000 newly designed compounds within 5 years and how this collaborative project, which involved all internal medicinal chemists using a crowd-sourcing approach, along with selected external partners, reached this ambitious goal.

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